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AnaptysBio, Inc., a clinical stage biotechnology company, engages in developing therapeutic product candidates for inflammation and immuno-oncology indications. Its products include Imsidolimab, an antibody that inhibits the interleukin-36 receptor (IL-36R) for the treatment of various dermatological inflammatory diseases; Rosnilimab, an anti-PD-1 agonist antibody program designed to augment PD-1 signaling through rosnilimab treatment to suppress T-cell driven human inflammatory diseases; and ANB032, an anti-BTLA modulator antibody applicable to human inflammatory diseases associated with lymphoid and myeloid immune cell dysregulation. The company also focuses on developing various antibody programs that are advanced to preclinical and clinical milestones under its collaborations. It has a collaboration and license agreement with GlaxoSmithKline, Inc. and Bristol-Myers Squibb; and license agreements with United Kingdom Research and Innovation, as well as Millipore Corporation. The company was formerly known as Anaptys Biosciences, Inc. and changed its name to AnaptysBio, Inc. in July 2006. AnaptysBio, Inc. was incorporated in 2005 and is based in San Diego, California.

AnaptysBio, Inc.

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ANNOUNCED INTENT TO SEPARATE BIOPHARMA OPERATIONS FROM SUBSTANTIAL ROYALTY ASSETS BY YE 2026 PHASE 2 TOP-LINE DATA THROUGH WEEK 12 FOR ROSNILIMAB, A PATHOGENIC T CELL DEPLETER, IN ULCERATIVE COLITIS ON TRACK FOR NOV./DEC. 2025 PHASE 2B DATA FOR ROSNILIMAB IN RHEUMATOID ARTHRITIS FEATURED AS LATE-BREAKING ORAL PRESENTATION AT ACR CONVERGENCE 2025 PHASE 1B INITIATED IN CELIAC DISEASE FOR ANB033, A CD122 ANTAGONIST; TOP-LINE PHASE 1B DATA ANTICIPATED IN Q4 2026 GSK ANNOUNCED STRONG COMMERCIAL PERFORMANCE FOR JEMPERLI, GROWING >16% QUARTER-OVER-QUARTER TO $303 MILLION IN Q3 2025 AND $785 MILLION YTD 2025 ANAPTYS ANTICIPATES ACCRUING A ONE-TIME $75 MILLION COMMERCIAL SALES MILESTONE IN Q4 2025 FROM GSK ONCE JEMPERLI ACHIEVES $1 BILLION IN WORLDWIDE NET SALES >$390 MILLION IN ANNUALIZED JEMPERLI ROYALTIES PAYABLE TO ANAPTYS AT GSK'S PEAK SALES GUIDANCE OF >$2.7 BILLION, WHICH ANAPTYS EXPECTS TO BE ACHIEVED BEFORE 2031 SAN DIEGO, NOV. 04, 2025 (GLOBE NEWSWIRE) -- ANAPTYSBIO, INC. (NASDAQ: ANAB), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY FOCUSED ON DELIVERING INNOVATIVE IMMUNOLOGY THERAPEUTICS, TODAY REPORTED FINANCIAL RESULTS FOR THE THIRD QUARTER ENDED SEPTEMBER 30, 2025, AND PROVIDED A BUSINESS UPDATE. OUR INTENT TO SEPARATE OUR WHOLLY OWNED BIOPHARMA PROGRAMS FROM OUR ROYALTY ASSETS PROVIDES INVESTORS WITH THE OPPORTUNITY TO REALIZE AND ENHANCE THE POTENTIAL VALUE OF TWO DISTINCT SETS OF ASSETS.

ANAPTYS ANNOUNCES THIRD QUARTER 2025 FINANCIAL RESULTS AND PROVIDES BUSINESS UPDATE

SAN DIEGO, NOV. 04, 2025 (GLOBE NEWSWIRE) -- ANAPTYSBIO, INC. (NASDAQ: ANAB), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY FOCUSED ON DELIVERING INNOVATIVE IMMUNOLOGY THERAPEUTICS, TODAY ANNOUNCED THAT DANIEL FAGA, PRESIDENT AND CHIEF EXECUTIVE OFFICER OF ANAPTYS, AND/OR OTHER MEMBERS OF ITS EXECUTIVE LEADERSHIP TEAM, ARE SCHEDULED TO PARTICIPATE IN MULTIPLE UPCOMING INVESTOR CONFERENCES: TD COWEN IMMUNOLOGY & INFLAMMATION SUMMIT, VIRTUAL FORMAT  FIRESIDE CHAT DATE AND TIME  WEDNESDAY, NOV. 12, 2025 AT 8:00AM ET GUGGENHEIM 2ND ANNUAL HEALTHCARE INNOVATION CONFERENCE, BOSTON, MA FORMAT  FIRESIDE CHAT AND 1X1 INVESTOR MEETINGS DATE AND TIME  WEDNESDAY, NOV. 12, 2025 AT 11:30AM ET STIFEL 2025 HEALTHCARE CONFERENCE, NEW YORK, NY FORMAT  FIRESIDE CHAT AND 1X1 INVESTOR MEETINGS DATE AND TIME  THURSDAY, NOV. 13, 2025 AT 1:20PM ET JEFFERIES GLOBAL HEALTHCARE CONFERENCE, LONDON, UK FORMAT  PRESENTATION AND 1X1 INVESTOR MEETINGS DATE AND TIME  MONDAY, NOV. 17, 2025 AT 4:00PM GMT LIVE WEBCASTS OF THE FIRESIDE CHATS AND PRESENTATION WILL BE AVAILABLE ON THE INVESTOR SECTION OF THE ANAPTYS WEBSITE ATHTTPS://IR.ANAPTYSBIO.COM/PRESENTATIONS-AND-EVENTS. REPLAYS OF THE WEBCASTS WILL BE AVAILABLE FOR AT LEAST 30 DAYS FOLLOWING THE EVENTS.

ANAPTYS ANNOUNCES PARTICIPATION IN NOVEMBER INVESTOR CONFERENCES

SAN DIEGO, OCT. 29, 2025 (GLOBE NEWSWIRE) -- ANAPTYSBIO, INC. (NASDAQ: ANAB), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY FOCUSED ON DELIVERING INNOVATIVE IMMUNOLOGY THERAPEUTICS, TODAY ANNOUNCED LATE-BREAKING DATA FROM THE ROBUST, GLOBAL 424-PATIENT PHASE 2B TRIAL OF ROSNILIMAB, A SELECTIVE AND POTENT PATHOGENIC T CELL DEPLETER, IN RHEUMATOID ARTHRITIS (RA) AT THE AMERICAN COLLEGE OF RHEUMATOLOGY (ACR) CONVERGENCE 2025 IN CHICAGO. NEW STUDY RESULTS SHOWED THAT POSITIVE WEEK 12 DATA ACROSS MULTIPLE HIGHER-ORDER RESPONSE MEASURES CONTINUE TO DEEPEN INTO WEEK 28 REGARDLESS OF PRIOR TREATMENT. THESE RESULTS WERE THEN DURABLE FOR AT LEAST THREE MONTHS OFF DRUG. ADDITIONALLY, ROSNILIMAB WAS WELL-TOLERATED WITH NO TREATMENT-RELATED SERIOUS ADVERSE EVENTS AND NO MALIGNANCIES IN ROSNILIMAB-TREATED PATIENTS THROUGH END-OF-TRIAL FOLLOW-UP (WEEK 38).

ANAPTYS ANNOUNCES NEW POSITIVE PHASE 2B TRIAL RESULTS FOR ROSNILIMAB IN RHEUMATOID ARTHRITIS AT ACR LATE-BREAKING ORAL PRESENTATION

SAN DIEGO, OCT. 13, 2025 (GLOBE NEWSWIRE) -- ANAPTYSBIO, INC. (NASDAQ: ANAB), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY FOCUSED ON DELIVERING INNOVATIVE IMMUNOLOGY THERAPEUTICS, TODAY ANNOUNCED THAT COMPLETE DATA FROM THE PHASE 2B TRIAL OF ROSNILIMAB, A PATHOGENIC T CELL DEPLETER, IN RHEUMATOID ARTHRITIS (RA), WAS ACCEPTED FOR A LATE-BREAKING ORAL PRESENTATION AT AMERICAN COLLEGE OF RHEUMATOLOGY (ACR) CONVERGENCE 2025 IN CHICAGO, IL, OCT. 24  29, 2025.

ANAPTYS ANNOUNCES LATE-BREAKING ORAL PRESENTATION OF COMPLETE PHASE 2B DATA FOR ROSNILIMAB IN RHEUMATOID ARTHRITIS AT UPCOMING ACR CONVERGENCE 2025

SAN DIEGO, SEPT. 29, 2025 (GLOBE NEWSWIRE) -- ANAPTYSBIO, INC. (NASDAQ: ANAB), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY FOCUSED ON DELIVERING INNOVATIVE IMMUNOLOGY THERAPEUTICS, TODAY ANNOUNCED IT WILL HOST A VIRTUAL INVESTOR EVENT ON ANB033, ITS CD122 ANTAGONIST, AT 4:30PM ET / 1:30PM PT ON TUESDAY, OCT. 14.

ANAPTYS TO PROVIDE OVERVIEW OF ANB033, A CD122 ANTAGONIST, AT VIRTUAL INVESTOR EVENT ON TUESDAY, OCT. 14

SAN DIEGO, SEPT. 29, 2025 (GLOBE NEWSWIRE) -- ANAPTYSBIO, INC. (NASDAQ: ANAB), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY FOCUSED ON DELIVERING INNOVATIVE IMMUNOLOGY THERAPEUTICS, ANNOUNCED TODAY THAT ITS BOARD OF DIRECTORS APPROVED PLANS TO EXPLORE SEPARATING ITS BUSINESS INTO TWO INDEPENDENT, PUBLICLY TRADED COMPANIES, EACH POISED FOR STRONG, SUSTAINABLE GROWTH. REFERRED TO AS ROYALTY MANAGEMENT CO AND AS BIOPHARMA CO IN THIS PRESS RELEASE, THE TWO COMPANIES' DIFFERENT BUSINESS MODELS ENABLE INVESTORS TO ALIGN THEIR INVESTMENT PHILOSOPHIES AND PORTFOLIO ALLOCATION WITH THE STRATEGIC OPPORTUNITIES AND FINANCIAL OBJECTIVES OF EACH COMPANY. ANAPTYS IS STRATEGICALLY POSITIONED WITH MULTIPLE ATTRACTIVE, HIGH-POTENTIAL ASSETS, INCLUDING OUR DEVELOPMENT-STAGE PIPELINE CONSISTING OF ROSNILIMAB, ANB033 AND ANB101, AS WELL AS SUBSTANTIAL POTENTIAL ROYALTIES AND MILESTONES PAYMENTS FROM OUR ONGOING FINANCIAL COLLABORATIONS WITH GSK AND VANDA, SAID DANIEL FAGA, PRESIDENT AND CHIEF EXECUTIVE OFFICER OF ANAPTYS. IN PARALLEL WITH ASSESSING MULTIPLE STRATEGIC OPTIONS FOR ROSNILIMAB IN RA OR UC, INCLUDING SECURING A GLOBAL PARTNERSHIP TO HELP ADVANCE DEVELOPMENT IN ALL INDICATIONS OR ADVANCING IN ONE PHASE 3 INDICATION INDEPENDENTLY, TODAY'S ANNOUNCEMENT TO EXPLORE A SEPARATION OF OUR WHOLLY OWNED BIOPHARMA PROGRAMS FROM OUR ROYALTY ASSETS IS INTENDED TO PROVIDE INVESTORS WITH THE OPPORTUNITY TO REALIZE AND ENHANCE THE POTENTIAL VALUE OF TWO DISTINCT SETS OF ASSETS. ROYALTY MANAGEMENT CO PROFILE

ANAPTYS ANNOUNCES INTENT TO SEPARATE BIOPHARMA OPERATIONS FROM SUBSTANTIAL ROYALTY ASSETS BY YEAR-END 2026

SAN DIEGO, AUG. 27, 2025 (GLOBE NEWSWIRE) -- ANAPTYSBIO, INC. (NASDAQ: ANAB), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY FOCUSED ON DELIVERING INNOVATIVE IMMUNOLOGY THERAPEUTICS, TODAY ANNOUNCED THAT DANIEL FAGA, PRESIDENT AND CHIEF EXECUTIVE OFFICER OF ANAPTYS, AND/OR OTHER MEMBERS OF ITS EXECUTIVE LEADERSHIP TEAM, ARE SCHEDULED TO PARTICIPATE IN MULTIPLE UPCOMING INVESTOR CONFERENCES: CANTOR GLOBAL HEALTHCARE CONFERENCE 2025,NEW YORK, NY FORMAT  FIRESIDE CHAT AND ONE-ON-ONE INVESTOR MEETINGS DATE AND TIME WEDNESDAY, SEPT. 3, 2025AT8:00AM ET/5:00AM PT 2025 WELLS FARGO HEALTHCARE CONFERENCE,BOSTON, MA FORMAT  FIRESIDE CHAT AND ONE-ON-ONE INVESTOR MEETINGS DATE AND TIME THURSDAY, SEPT.

ANAPTYS ANNOUNCES PARTICIPATION IN SEPTEMBER INVESTOR CONFERENCES

SAN DIEGO, AUG. 06, 2025 (GLOBE NEWSWIRE) -- ANAPTYSBIO, INC. (NASDAQ: ANAB), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY FOCUSED ON DELIVERING INNOVATIVE IMMUNOLOGY THERAPEUTICS, TODAY REPORTED FINANCIAL RESULTS FOR THE SECOND QUARTER ENDED JUNE 30, 2025, AND PROVIDED A BUSINESS UPDATE.

ANAPTYS ANNOUNCES SECOND QUARTER 2025 FINANCIAL RESULTS AND PROVIDES BUSINESS UPDATE

SAN DIEGO, JUNE 03, 2025 (GLOBE NEWSWIRE) -- ANAPTYSBIO, INC. (NASDAQ: ANAB), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY FOCUSED ON DELIVERING INNOVATIVE IMMUNOLOGY THERAPEUTICS, TODAY ANNOUNCED THAT INVESTIGATIONAL ROSNILIMAB, A DEPLETER AND AGONIST TARGETING PD-1+ T CELLS, DEMONSTRATED A BEST-IN-DISEASE PROFILE IN PATIENTS WITH MODERATE-TO-SEVERE RHEUMATOID ARTHRITIS (RA). IN THE ROBUST, GLOBAL 424-PATIENT PHASE 2B TRIAL, ROSNILIMAB ACHIEVED JAK-LIKE EFFICACY ON MULTIPLE CLINICALLY MEANINGFUL MEASURES, INCLUDING LOW DISEASE ACTIVITY (LDA) AND REMISSION ON THE CLINICAL DISEASE ACTIVITY INDEX (CDAI), AS WELL AS ACR70 RESPONSE, OVER A SIX-MONTH PERIOD. FURTHERMORE, RESPONSES WERE THEN DURABLE FOR AT LEAST TWO MONTHS OFF DRUG. ROSNILIMAB WAS SAFE AND WELL TOLERATED, PARTICULARLY WHEN COMPARED TO STANDARD OF CARE BIOLOGICS OR JAKS.

ANAPTYS ANNOUNCES POSITIVE ROSNILIMAB DATA UPDATED THROUGH SIX MONTHS IN ROBUST PHASE 2B TRIAL IN RA

SAN DIEGO, MAY 27, 2025 (GLOBE NEWSWIRE) -- ANAPTYSBIO, INC. (NASDAQ: ANAB), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY FOCUSED ON DELIVERING INNOVATIVE IMMUNOLOGY THERAPEUTICS, WILL HOST AN INVESTOR CALL AND LIVE WEBCAST TO REVIEW UPDATED DATA FROM THE GLOBAL PHASE 2B RENOIR CLINICAL TRIAL OF INVESTIGATIONAL ROSNILIMAB, A DEPLETER AND AGONIST TARGETING PD-1+ T CELLS, FOR MODERATE-TO-SEVERE RHEUMATOID ARTHRITIS ON TUESDAY, JUNE 3, 2025, AT 4:15PM ET / 1:15PM PT.

AnaptysBio, Inc.

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