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HCW Biologics Inc., a preclinical stage biopharmaceutical company, focuses on discovering and developing novel immunotherapies for chronic, low-grade inflammation, and age-related diseases. The company's lead products include HCW9218, which is an injectable immunotherapeutic for patients with pancreatic, ovarian, breast, prostate, and colorectal cancers, as well as pulmonary fibrosis; and HCW9302 for auto-immune diseases, such as alopecia areata and metabolic diseases. It also develops HCW9201, a cell-based therapy that is in Phase II clinical trials for the treatment of patients with relapsed/refractory acute myeloid leukemia; and HCW9206 for the treatment of acute myeloid leukemia. The company was incorporated in 2018 and is headquartered in Miramar, Florida.

HCW Biologics Inc.

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FIRST PATIENT DOSED AT THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER IN THIS MULTI-CENTER TRIAL ACTIVE COMPONENT OF HCW9302 IS INTERLEUKIN-2 -- CYTOKINE THAT MAINTAINS PROPER NUMBERS AND FUNCTIONS OF REGULATORY T CELLS TO CONTROL EXCESSIVE INFLAMMATION GATEWAY TO DEVELOPMENT OF A FIRST-IN-KIND IMMUNOTHERAPEUTIC FOR AUTOIMMUNE AND PRO-INFLAMMATORY DISEASES MIRAMAR, FLA., NOV. 18, 2025 (GLOBE NEWSWIRE) -- HCW BIOLOGICS INC. (HCWB OR THE COMPANY) (NASDAQ: HCWB), A U.S.-BASED CLINICAL-STAGE BIOPHARMACEUTICAL COMPANY FOCUSED ON DISCOVERING AND DEVELOPING INNOVATIVE IMMUNOTHERAPIES TO EXTEND HEALTHSPAN BY TARGETING THE LINK BETWEEN CHRONIC INFLAMMATION AND DISEASE, TODAY ANNOUNCED THE FIRST PATIENT WAS DOSED AT THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER FOR THE COMPANY-SPONSORED, MULTI-CENTER FIRST-IN-HUMAN CLINICAL TRIAL TO EVALUATE HCW9302 IN PATIENTS WITH ALOPECIA AREATA (NCT07049328).

HCW BIOLOGICS ANNOUNCES INITIATION OF FIRST-IN-HUMAN CLINICAL TRIAL TO EVALUATE HCW9302 IN AN AUTOIMMUNE DISEASE

MIRAMAR, FLA., NOV. 14, 2025 (GLOBE NEWSWIRE) -- HCW BIOLOGICS INC. (THE COMPANY OR HCW BIOLOGICS) (NASDAQ: HCWB), A CLINICAL-STAGE BIOPHARMACEUTICAL COMPANY FOCUSED ON DISCOVERING AND DEVELOPING NOVEL IMMUNOTHERAPIES TO LENGTHEN HEALTHSPAN BY DISRUPTING THE LINK BETWEEN INFLAMMATION AND DISEASES, TODAY REPORTED FINANCIAL RESULTS AND RECENT BUSINESS HIGHLIGHTS FOR ITS THIRD QUARTER ENDED SEPTEMBER 30, 2025.

HCW BIOLOGICS REPORTS THIRD QUARTER 2025 BUSINESS HIGHLIGHTS AND FINANCIAL RESULTS

TETRA-VALENT T-CELL ENGAGER DESIGNED TO ADDRESS SHORTFALLS OF BI-SPECIFIC T-CELL ENGAGERS (BITE) RELATED TO MANUFACTURABILITY, SAFETY PROFILE, AND ABILITY TO TREAT A WIDE SPECTRUM OF SOLID TUMORS TETRA-VALENT T-CELL ENGAGER DESIGNED TO ADDRESS SHORTFALLS OF BI-SPECIFIC T-CELL ENGAGERS (BITE) RELATED TO MANUFACTURABILITY, SAFETY PROFILE, AND ABILITY TO TREAT A WIDE SPECTRUM OF SOLID TUMORS

HCW BIOLOGICS PRESENTS PRECLINICAL DATA FOR TRBC-BASED T-CELL ENGAGER PROGRAM AT THE SOCIETY FOR IMMUNOTHERAPY OF CANCER'S (SITC) 40TH ANNUAL MEETING

MIRAMAR, FLA., OCT. 16, 2025 (GLOBE NEWSWIRE) -- HCW BIOLOGICS INC. (THE COMPANY) (NASDAQ: HCWB), A U.S.-BASED CLINICAL-STAGE BIOPHARMACEUTICAL COMPANY FOCUSED ON DISCOVERING AND DEVELOPING INNOVATIVE IMMUNOTHERAPIES TO EXTEND HEALTHSPAN BY TARGETING THE LINK BETWEEN CHRONIC INFLAMMATION AND DISEASE, IS PLEASED TO ANNOUNCE ITS PARTICIPATION IN THE UPCOMING 2025 MAXIM GROWTH SUMMIT, TAKING PLACE FROM OCTOBER 22ND TO 23RD AT THE HARD ROCK HOTEL NYC. THIS PRESTIGIOUS EVENT BRINGS TOGETHER INDUSTRY LEADERS, INNOVATORS, AND PREMIER INSTITUTIONS TO EXPLORE THE LATEST TRENDS AND ADVANCEMENTS ACROSS SEVERAL INDUSTRIES.

HCW BIOLOGICS TO PARTICIPATE IN THE 2025 MAXIM GROWTH SUMMIT

HCW BIOLOGICS INC. (NASDAQ: HCWB) PARTICIPATES IN VIRTUAL INVESTOR WHAT THIS MEANS SEGMENT ABOUT ITS PROPRIETARY T-CELL ENGAGER PROGRAM

WUGEN CLOSED A $115 MILLION EQUITY FINANCING LED BY FIDELITY MANAGEMENT & RESEARCH COMPANY HCW BIOLOGICS HOLDS A MINORITY EQUITY INTEREST IN WUGEN MIRAMAR, FLA., SEPT. 18, 2025 (GLOBE NEWSWIRE) -- HCW BIOLOGICS INC. (THE COMPANY OR HCW BIOLOGICS), (NASDAQ: HCWB), A U.S.-BASED CLINICAL-STAGE BIOPHARMACEUTICAL COMPANY FOCUSED ON DISCOVERING AND DEVELOPING NOVEL IMMUNOTHERAPIES TO LENGTHEN HEALTHSPAN BY DISRUPTING THE LINK BETWEEN INFLAMMATION AND AGE-RELATED DISEASES, CONGRATULATES WUGEN, INC. (WUGEN) ON ITS RECENTLY ANNOUNCED $115 MILLION EQUITY FINANCING LED BY FIDELITY MANAGEMENT & RESEARCH COMPANY, WITH PARTICIPATION FROM RIVERVEST VENTURE PARTNERS, LIGHTCHAIN CAPITAL, ABINGWORTH, ICG, LYZZ CAPITAL, TYBOURNE CAPITAL MANAGEMENT, AISLING CAPITAL MANAGEMENT, AND OTHER LEADING LIFE SCIENCES INVESTORS.

HCW BIOLOGICS, A SHAREHOLDER OF WUGEN, CONGRATULATES WUGEN ON ITS RECENT SUCCESSFUL EQUITY FINANCING

LEAD PRODUCT CANDIDATE WILL BE ADVANCED TO LATE IND-ENABLING STUDIES TO PREPARE FOR CLINICAL TRIALS FOR EVALUATION IN THE TREATMENT OF SOLID TUMORS

HCW BIOLOGICS DESIGNATES ONE OF ITS PROPRIETARY TRBC-PEMBROLIZUMAB-BASED IMMUNE CHECKPOINT INHIBITORS AS ITS FRANCHISE IMMUNOTHERAPEUTIC FOR INTERNAL CLINICAL DEVELOPMENT

COMPANY'S PEMBROLIZUMAB-BASED IMMUNE CHECKPOINT INHIBITOR EXHIBITED SUCCESS AGAINST SOLID TUMORS IN IND-ENABLING STUDIES BY SIMULTANEOUSLY ACTIVATING IMMUNE CELLS AND PROMOTING THEIR INFILTRATION INTO SOLID TUMORS PRESENTATION AT NOVA SOUTHEASTERN UNIVERSITY ON SEPTEMBER 12, 2025, IN FORT LAUDERDALE, FLORIDA MIRAMAR, FLA., AUG. 25, 2025 (GLOBE NEWSWIRE) -- HCW BIOLOGICS INC. (THE COMPANY OR HCW BIOLOGICS), (NASDAQ: HCWB), A U.S.-BASED CLINICAL-STAGE BIOPHARMACEUTICAL COMPANY FOCUSED ON DISCOVERING AND DEVELOPING NOVEL IMMUNOTHERAPIES TO LENGTHEN HEALTHSPAN BY DISRUPTING THE LINK BETWEEN INFLAMMATION AND AGE-RELATED DISEASES, ANNOUNCED TODAY THAT ITS SCIENTISTS HAVE SUCCESSFULLY DEVELOPED SECOND-GENERATION, PEMBROLIZUMAB-BASED IMMUNOTHERAPEUTICS AGAINST SOLID TUMORS, PARTICULARLY FOR PANCREATIC AND OVARIAN CANCER, USING ITS NOVEL PROPRIETARY TRBC PRODUCT DISCOVERY AND DEVELOPMENT PLATFORM TECHNOLOGY.

HCW BIOLOGICS TO SHOWCASE ITS NOVEL SECOND-GENERATION IMMUNE CHECKPOINT INHIBITOR IDENTIFIED AS A POTENTIAL GATEWAY TO A MULTI-BILLION DOLLAR MARKET

MIRAMAR, FLA., AUG. 18, 2025 (GLOBE NEWSWIRE) -- HCW BIOLOGICS INC. (THE COMPANY OR HCW BIOLOGICS) (NASDAQ: HCWB), A CLINICAL-STAGE BIOPHARMACEUTICAL COMPANY FOCUSED ON DISCOVERING AND DEVELOPING NOVEL IMMUNOTHERAPIES TO LENGTHEN HEALTH SPAN BY DISRUPTING THE LINK BETWEEN INFLAMMATION AND AGE-RELATED DISEASES, TODAY REPORTED FINANCIAL RESULTS AND RECENT BUSINESS HIGHLIGHTS FOR ITS SECOND QUARTER ENDED JUNE 30, 2025.

HCW BIOLOGICS REPORTS SECOND QUARTER 2025BUSINESS HIGHLIGHTS AND FINANCIAL RESULTS

TETRA-FUNCTIONAL T-CELL ENGAGERS ACTIVATE T CELLS AND SIMULTANEOUSLY REDUCE IMMUNOSUPPRESSION, WITH POTENT AND ANTIGEN-SPECIFIC ANTI-PANCREATIC CANCER ACTIVITIES AT DOSE LEVELS THAT ARE WELL TOLERATED

HCW BIOLOGICS TO SHOWCASE IMPORTANT UPDATES ON IND-ENABLING STUDIES AND PRECLINICAL SUCCESS OF ITS NOVEL MULTI-SPECIFIC T-CELL ENGAGERS AGAINST SOLID TUMORS

HCW Biologics Inc.

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