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Immunic, Inc., a clinical-stage biopharmaceutical company, develops a pipeline of selective oral immunology therapies for the treatment of chronic inflammatory and autoimmune diseases. Its lead development program is IMU-838, which is in Phase 2 clinical for treatment of relapsing-remitting multiple sclerosis, inflammatory bowel disease, and other chronic inflammatory and autoimmune diseases, as well as to treat coronavirus disease. The company is also developing IMU-935, an inverse agonist of ROR?t; and IMU-856 for the restoration of the intestinal barrier function in patients suffering from diseases, such as inflammatory bowel disease, irritable bowel syndrome with diarrhea, immune checkpoint inhibitor induced colitis, and other intestinal barrier function diseases. Immunic, Inc. is headquartered in New York, New York.

Immunic, Inc.

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NEW YORK , OCT. 29, 2025 /PRNEWSWIRE/ -- IMMUNIC, INC. (NASDAQ: IMUX),A BIOTECHNOLOGY COMPANY DEVELOPING A CLINICAL PIPELINE OF ORALLY ADMINISTERED, SMALL MOLECULE THERAPIES FOR CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES, TODAY ANNOUNCED PARTICIPATION IN THE FOLLOWING INDUSTRY AND INVESTOR CONFERENCES IN NOVEMBER: NOVEMBER 3-5:BIO-EUROPE. DANIEL VITT, PH.D.

IMMUNIC TO PARTICIPATE IN INDUSTRY AND INVESTOR CONFERENCES IN NOVEMBER

NEW YORK , OCT. 1, 2025 /PRNEWSWIRE/ -- IMMUNIC, INC. (NASDAQ: IMUX),A BIOTECHNOLOGY COMPANY DEVELOPING A CLINICAL PIPELINE OF ORALLY ADMINISTERED, SMALL MOLECULE THERAPIES FOR CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES, TODAY ANNOUNCED PARTICIPATION IN THE FOLLOWING SCIENTIFIC AND INVESTOR CONFERENCES IN OCTOBER: OCTOBER 4-7: UEGW 2025  UNITED EUROPEAN GASTROENTEROLOGY WEEK. IMMUNIC'S R&D TEAM WILL ATTEND THIS CONFERENCE IN BERLIN, GERMANY.

IMMUNIC TO PARTICIPATE IN SCIENTIFIC AND INVESTOR CONFERENCES IN OCTOBER

 VIDOFLUDIMUS CALCIUM DEMONSTRATED STATISTICALLY SIGNIFICANT 24-WEEK CONFIRMED DISABILITY IMPROVEMENT IN PHASE 2 CALLIPER TRIAL IN PROGRESSIVE MULTIPLE SCLEROSIS, WITH OVER TWO-FOLD PROBABILITY OVER PLACEBO IN THE OVERALL STUDY POPULATION AND CONSISTENT EFFECTS ACROSS SUBTYPES   CALLIPER DATA SHOWED POSITIVE AND CONSISTENT SIGNALS FOR SLOWING DISABILITY PROGRESSION ACROSS DISABILITY ENDPOINTS, PATIENT POPULATIONS AND SUBGROUPS WITHOUT EVIDENCE OF FOCAL INFLAMMATION, REINFORCING THE DRUG'S NEUROPROTECTIVE POTENTIAL AND PROMISE TO SLOW DISEASE PROGRESSION   CALLIPER DATA SUPPORTS NURR1 ACTIVATION AS NEW MECHANISM TO PREVENT NEURODEGENERATION IN MULTIPLE SCLEROSIS   LONG-TERM DATA FROM PHASE 2 EMPHASIS TRIAL IN RELAPSING-REMITTING MULTIPLE SCLEROSIS SHOWED HIGH RATES OF PATIENTS REMAINING FREE OF 12- AND 24-WEEK CONFIRMED DISABILITY WORSENING AS WELL AS LOW DISCONTINUATION RATES AND FAVORABLE LONG-TERM SAFETY AND TOLERABILITY  NEW YORK , SEPT. 25, 2025 /PRNEWSWIRE/ -- IMMUNIC, INC. (NASDAQ: IMUX),A BIOTECHNOLOGY COMPANY DEVELOPING A CLINICAL PIPELINE OF ORALLY ADMINISTERED, SMALL MOLECULE THERAPIES FOR CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES, TODAY ANNOUNCED THE PRESENTATION OF KEY DATA IN AN ORAL AND FOUR POSTER PRESENTATIONS, INCLUDING ONE LATE-BREAKING POSTER, AT THE 41ST CONGRESS OF THE EUROPEAN COMMITTEE FOR TREATMENT AND RESEARCH IN MULTIPLE SCLEROSIS (ECTRIMS), BEING HELD SEPTEMBER 24-26, 2025 IN BARCELONA, SPAIN.

IMMUNIC PRESENTED KEY VIDOFLUDIMUS CALCIUM DATA AT THE 41ST CONGRESS OF ECTRIMS, HIGHLIGHTING ITS POTENTIAL IN MULTIPLE SCLEROSIS

 FIFTH U.S. PATENT DIRECTED TO USE OF VIDOFLUDIMUS CALCIUM IN MULTIPLE SCLEROSIS   COMPREHENSIVE INTELLECTUAL PROPERTY STRATEGY SECURES PROTECTION INTO 2041 IN THE U.S., UNLESS EXTENDED FURTHER  NEW YORK , SEPT. 9, 2025 /PRNEWSWIRE/ -- IMMUNIC, INC. (NASDAQ: IMUX),A BIOTECHNOLOGY COMPANY DEVELOPING A CLINICAL PIPELINE OF ORALLY ADMINISTERED, SMALL MOLECULE THERAPIES FOR CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES, TODAY ANNOUNCED THAT IT HAS RECEIVED A NOTICE OF ALLOWANCE FROM THE UNITED STATES PATENT AND TRADEMARK OFFICE (USPTO) FOR PATENT APPLICATION 18/529,946, ENTITLED, "TREATMENT OF MULTIPLE SCLEROSIS COMPRISING DHODH INHIBITORS.

IMMUNIC RECEIVES NOTICE OF ALLOWANCE FOR UNITED STATES PATENT PROTECTING VIDOFLUDIMUS CALCIUM'S DOSE STRENGTHS IN PROGRESSIVE MULTIPLE SCLEROSIS

NEW YORK , SEPT. 4, 2025 /PRNEWSWIRE/ -- IMMUNIC, INC. (NASDAQ: IMUX),A BIOTECHNOLOGY COMPANY DEVELOPING A CLINICAL PIPELINE OF ORALLY ADMINISTERED, SMALL MOLECULE THERAPIES FOR CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES, TODAY ANNOUNCED PARTICIPATION IN THE FOLLOWING INVESTOR AND SCIENTIFIC CONFERENCES IN SEPTEMBER: SEPTEMBER 8-10: H.C.

IMMUNIC TO PARTICIPATE IN INVESTOR AND SCIENTIFIC CONFERENCES IN SEPTEMBER

 VIDOFLUDIMUS CALCIUM SUBSTANTIALLY REDUCED 24-WEEK CONFIRMED DISABILITY WORSENING IN PHASE 2 CALLIPER TRIAL IN OVERALL PROGRESSIVE MULTIPLE SCLEROSIS STUDY POPULATION AND ACROSS SUBTYPES,REINFORCING THE DRUG'S NEUROPROTECTIVE POTENTIAL AND ABILITY TO SLOW DISEASE PROGRESSION   COMPLETED ENROLLMENT FOR BOTH PHASE 3 ENSURE TRIALS OF VIDOFLUDIMUS CALCIUM IN RELAPSING MULTIPLE SCLEROSIS; TOP-LINE DATA EXPECTED BY END OF 2026   NEW LONG-TERM OPEN-LABEL EXTENSION DATA FROM PHASE 2 EMPHASIS TRIAL IN RELAPSING-REMITTING MULTIPLE SCLEROSIS SHOWED HIGH RATES OF PATIENTS REMAINING FREE OF 12-WEEK AND 24-WEEK CONFIRMED DISABILITY WORSENING   STRENGTHENED BALANCE SHEET WITH TWO FINANCINGS TOTALING $70.1 MILLION IN GROSS PROCEEDS  NEW YORK , AUG. 7, 2025 /PRNEWSWIRE/ -- IMMUNIC, INC. (NASDAQ: IMUX),A BIOTECHNOLOGY COMPANY DEVELOPING A CLINICAL PIPELINE OF ORALLY ADMINISTERED, SMALL MOLECULE THERAPIES FOR CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES, TODAY ANNOUNCED FINANCIAL RESULTS FOR THE SECOND QUARTER AND SIX MONTHS ENDED JUNE 30, 2025, AND PROVIDED A CORPORATE UPDATE. "DURING THE SECOND QUARTER AND MORE RECENTLY, WE HAVE MADE SUBSTANTIAL CLINICAL PROGRESS IN ADVANCING OUR POTENTIALLY TRANSFORMATIVE LEAD ASSET, VIDOFLUDIMUS CALCIUM (IMU-838), AN ORALLY AVAILABLE NUCLEAR RECEPTOR-RELATED 1 (NURR1) ACTIVATOR," STATED DANIEL VITT, PH.D.

IMMUNIC, INC. REPORTS SECOND QUARTER 2025 FINANCIAL RESULTS AND PROVIDES CORPORATE UPDATE

 AT WEEK 144, 92.3% OF PATIENTS REMAINED FREE OF 12-WEEK CONFIRMED DISABILITY WORSENING (CDW) WITH 92.7% REMAINING FREE OF 24-WEEK CDW   VIDOFLUDIMUS CALCIUM CONTINUES TO DEMONSTRATE FAVORABLE SAFETY AND TOLERABILITY PROFILE; LONG-TERM DATA NOW AVAILABLE UP TO 5.5 YEARS  NEW YORK , JUNE 24, 2025 /PRNEWSWIRE/ -- IMMUNIC, INC. (NASDAQ: IMUX),A BIOTECHNOLOGY COMPANY DEVELOPING A CLINICAL PIPELINE OF ORALLY ADMINISTERED, SMALL MOLECULE THERAPIES FOR CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES, TODAY REPORTED NEW LONG-TERM OPEN-LABEL EXTENSION (OLE) DATA FROM ITS PHASE 2 EMPHASIS TRIAL OF LEAD ASSET,ORALLY AVAILABLE NUCLEAR RECEPTOR-RELATED 1 (NURR1) ACTIVATOR, VIDOFLUDIMUS CALCIUM (IMU-838), IN PATIENTS WITH RELAPSING-REMITTING MULTIPLE SCLEROSIS (RRMS). "IT IS MEANINGFUL TO SEE THAT PATIENTS TREATED WITH VIDOFLUDIMUS CALCIUM DURING THE OLE PERIOD OF OUR PHASE 2 EMPHASIS TRIAL IN RRMS EXPERIENCEDA LOW RATE OF CONFIRMED DISABILITY WORSENING (CDW) EVENTS, AS MEASURED BY THE EXPANDED DISABILITY STATUS SCALE (EDSS).

IMMUNIC REPORTS NEW, POSITIVE LONG-TERM OPEN-LABEL EXTENSION DATA FROM PHASE 2 EMPHASIS TRIAL OF VIDOFLUDIMUS CALCIUM IN RELAPSING-REMITTING MULTIPLE SCLEROSIS

 ENROLLMENT COMPLETED FOR BOTH PHASE 3 ENSURE TRIALS OF VIDOFLUDIMUS CALCIUM IN RELAPSING MULTIPLE SCLEROSIS; TOP-LINE DATA EXPECTED END OF 2026   ADDITIONAL DATA FROM PHASE 2 CALLIPER TRIAL IN PROGRESSIVE MULTIPLE SCLEROSIS FURTHER SUPPORTS THE RECENTLY RELEASED POSITIVE TOP-LINE RESULTS AND FURTHER UNDERLINES VIDOFLUDIMUS CALCIUM'S NEUROPROTECTIVE POTENTIAL   NEW CALLIPER DATA REGARDING TIME TO 24-WEEK CONFIRMED DISABILITY WORSENING SHOWS SUBSTANTIAL AND MEDICALLY RELEVANT REDUCTIONS FOR VIDOFLUDIMUS CALCIUM OVER PLACEBO IN THE OVERALL STUDY POPULATION AND MAJOR DISEASE SUBTYPES  NEW YORK , JUNE 5, 2025 /PRNEWSWIRE/ -- IMMUNIC, INC. (NASDAQ: IMUX),A BIOTECHNOLOGY COMPANY DEVELOPING A CLINICAL PIPELINE OF ORALLY ADMINISTERED, SMALL MOLECULE THERAPIES FOR CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES, ANNOUNCED THE COMPLETION OF ENROLLMENT FOR BOTH PHASE 3 ENSURE TRIALS OF LEAD ASSET, NUCLEAR RECEPTOR-RELATED 1 (NURR1) ACTIVATOR, VIDOFLUDIMUS CALCIUM (IMU-838), IN PATIENTS WITH RELAPSING MULTIPLE SCLEROSIS AND ADDITIONAL PHASE 2 CALLIPER TRIAL DATA IN PATIENTS WITH PROGRESSIVE MULTIPLE SCLEROSIS UNDERLINING THE RECENTLY RELEASED POSITIVE TOP-LINE RESULTS. ENROLLMENT COMPLETED FOR BOTH PHASE 3 ENSURE TRIALS IN RELAPSING MULTIPLE SCLEROSIS (RMS) THE ENSURE PROGRAM COMPRISES TWO IDENTICAL MULTICENTER, RANDOMIZED, DOUBLE-BLIND PHASE 3 TRIALS DESIGNED TO EVALUATE THE EFFICACY, SAFETY AND TOLERABILITY OF VIDOFLUDIMUS CALCIUM VERSUS PLACEBO IN RMS PATIENTS.

IMMUNIC ANNOUNCES COMPLETION OF ENROLLMENT FOR BOTH PHASE 3 ENSURE TRIALS IN RELAPSING MS AND PRESENTS ADDITIONAL DATA UNDERLINING POSITIVE OUTCOME OF PHASE 2 CALLIPER TRIAL IN PROGRESSIVE MS

NEW YORK , JUNE 3, 2025 /PRNEWSWIRE/ -- IMMUNIC, INC. ("IMMUNIC" OR THE "COMPANY") (NASDAQ: IMUX), A BIOTECHNOLOGY COMPANY DEVELOPING A CLINICAL PIPELINE OF ORALLY ADMINISTERED, SMALL MOLECULE THERAPIES FOR CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES, TODAY ANNOUNCED THE CLOSING OF ITS PREVIOUSLY ANNOUNCED UNDERWRITTEN PUBLIC OFFERING OF (I) PRE-FUNDED WARRANTS TO PURCHASE SHARES OF COMMON STOCK (THE "PRE-FUNDED WARRANTS"), (II) SERIES A WARRANTS TO PURCHASE SHARES OF COMMON STOCK (OR PRE-FUNDED WARRANTS) (THE "SERIES A WARRANTS"), AND (III) SERIES B WARRANTS TO PURCHASE SHARES OF COMMON STOCK (OR PRE-FUNDED WARRANTS) (THE "SERIES B WARRANTS"). THE PRE-FUNDED WARRANTS ARE IMMEDIATELY EXERCISABLE, AND MAY BE EXERCISED AT ANY TIME AFTER THEIR ORIGINAL ISSUANCE.

IMMUNIC, INC. ANNOUNCES CLOSING OF OVERSUBSCRIBED $65 MILLION UNDERWRITTEN PUBLIC OFFERING

NEW YORK , JUNE 2, 2025 /PRNEWSWIRE/ -- IMMUNIC, INC. (NASDAQ: IMUX),A BIOTECHNOLOGY COMPANY DEVELOPING A CLINICAL PIPELINE OF ORALLY ADMINISTERED, SMALL MOLECULE THERAPIES FOR CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES, TODAY ANNOUNCED PARTICIPATION IN THE FOLLOWING INVESTOR, SCIENTIFIC AND INDUSTRY CONFERENCES IN JUNE: JUNE 3-5:JEFFERIES HEALTHCARE CONFERENCE. DANIEL VITT, PH.D.

Immunic, Inc.

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