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Kymera Therapeutics, Inc., a biopharmaceutical company, focuses on discovering and developing novel small molecule therapeutics that selectively degrade disease-causing proteins by harnessing the body's own natural protein degradation system. It engages in developing IRAK4 program, which is in Phase I clinical trial for the treatment of immunology-inflammation diseases, including hidradenitis suppurativa, atopic dermatitis, macrophage activation syndrome, general pustular psoriasis, and rheumatoid arthritis; IRAKIMiD program to treat MYD88-mutated diffuse large B cell lymphoma; STAT3 program for the treatment of hematologic malignancies and solid tumors, as well as autoimmune diseases and fibrosis; and MDM2 program to treat hematological malignancies and solid tumors. The company was incorporated in 2015 and is headquartered in Watertown, Massachusetts.

Kymera Therapeutics, Inc.

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WATERTOWN, MASS., DEC. 08, 2025 (GLOBE NEWSWIRE) -- KYMERA THERAPEUTICS, INC. (NASDAQ: KYMR), A CLINICAL-STAGE BIOPHARMACEUTICAL COMPANY ADVANCING A NEW CLASS OF ORAL SMALL MOLECULE DEGRADER MEDICINES FOR IMMUNOLOGICAL DISEASES, TODAY ANNOUNCED THAT IT HAS COMMENCED AN UNDERWRITTEN PUBLIC OFFERING OF $500.0 MILLION OF SHARES OF ITS COMMON STOCK. ALL OF THE SHARES OF COMMON STOCK TO BE SOLD IN THIS OFFERING ARE BEING OFFERED BY KYMERA. IN ADDITION, KYMERA INTENDS TO GRANT THE UNDERWRITERS A 30-DAY OPTION TO PURCHASE UP TO AN ADDITIONAL $75.0 MILLION OF SHARES OF ITS COMMON STOCK AT THE PUBLIC OFFERING PRICE PER SHARE, LESS UNDERWRITING DISCOUNTS AND COMMISSIONS. THE PROPOSED OFFERING IS SUBJECT TO MARKET AND OTHER CONDITIONS, AND THERE CAN BE NO ASSURANCE AS TO WHETHER OR WHEN THE OFFERING MAY BE COMPLETED, OR AS TO THE ACTUAL SIZE OR TERMS OF THE OFFERING.

KYMERA THERAPEUTICS ANNOUNCES PROPOSED PUBLIC OFFERING

KT-621 ACHIEVED DEEP STAT6 DEGRADATION ACROSS BOTH THE 100 MG AND 200 MG DOSE GROUPS TESTED, WITH MEDIAN REDUCTIONS OF 94% AND 98% IN SKIN AND BLOOD, RESPECTIVELY, DEMONSTRATING STRONG TRANSLATION FROM HEALTHY VOLUNTEERS TO ATOPIC DERMATITIS (AD) PATIENTS

KYMERA THERAPEUTICS ANNOUNCES POSITIVE RESULTS FROM BROADEN PHASE 1B CLINICAL TRIAL OF KT-621, A FIRST-IN-CLASS, ORAL STAT6 DEGRADER, IN PATIENTS WITH MODERATE TO SEVERE ATOPIC DERMATITIS

COMPANY TO HOST VIDEO CONFERENCE CALL AND WEBCAST AT 8:00 A.M. ET ON MONDAY, DECEMBER 8, 2025 WATERTOWN, MASS.

KYMERA THERAPEUTICS TO ANNOUNCE KT-621 BROADEN PHASE 1B ATOPIC DERMATITIS TRIAL RESULTS ON DECEMBER 8, 2025

DATA FROM THE KT-621 BROADEN2 PHASE 2B AD PATIENT TRIAL EXPECTED TO BE REPORTED BY MID-2027 KT-621 BREADTH PHASE 2B TRIAL IN ASTHMA ON TRACK TO INITIATE IN 1Q26 COMPLETED DOSING IN KT-621 BROADEN PHASE 1B AD TRIAL WITH DATA TO BE REPORTED IN DECEMBER 2025 WATERTOWN, MASS., NOV. 25, 2025 (GLOBE NEWSWIRE) -- KYMERA THERAPEUTICS, INC. (NASDAQ: KYMR), A CLINICAL-STAGE BIOPHARMACEUTICAL COMPANY ADVANCING A NEW CLASS OF ORAL SMALL MOLECULE DEGRADER MEDICINES FOR IMMUNOLOGICAL DISEASES, TODAY ANNOUNCED THAT IT RECENTLY INITIATED DOSING IN ITS BROADEN2 PHASE 2B CLINICAL TRIAL EVALUATING KT-621, AN ORAL, HIGHLY SELECTIVE, POTENT DEGRADER OF STAT6, IN PATIENTS WITH MODERATE TO SEVERE ATOPIC DERMATITIS (AD).

KYMERA THERAPEUTICS ANNOUNCES FIRST PATIENT DOSED IN BROADEN2 PHASE 2B ATOPIC DERMATITIS CLINICAL TRIAL OF KT-621, A FIRST-IN-CLASS, ORAL STAT6 DEGRADER

WATERTOWN, MASS., NOV. 24, 2025 (GLOBE NEWSWIRE) -- KYMERA THERAPEUTICS, INC.(NASDAQ: KYMR), A CLINICAL-STAGE BIOPHARMACEUTICAL COMPANY ADVANCING A NEW CLASS OF ORAL SMALL MOLECULE DEGRADER MEDICINES FOR IMMUNOLOGICAL DISEASES, TODAY ANNOUNCED THAT THE COMPANY WILL PARTICIPATE IN FIRESIDE CHATS AT THE FOLLOWING UPCOMING INVESTOR EVENTS:

KYMERA THERAPEUTICS TO PARTICIPATE IN UPCOMING DECEMBER INVESTOR CONFERENCES

WATERTOWN, MASS., NOV. 03, 2025 (GLOBE NEWSWIRE) -- KYMERA THERAPEUTICS, INC. (NASDAQ: KYMR), A CLINICAL-STAGE BIOPHARMACEUTICAL COMPANY ADVANCING A NEW CLASS OF ORAL SMALL MOLECULE DEGRADER MEDICINES FOR IMMUNOLOGICAL DISEASES, TODAY ANNOUNCED THAT THE COMPANY WILL PARTICIPATE IN FIRESIDE CHATS AT THE FOLLOWING UPCOMING INVESTOR EVENTS:

KYMERA THERAPEUTICS TO PARTICIPATE IN UPCOMING NOVEMBER INVESTOR CONFERENCES

WATERTOWN, MASS., OCT. 28, 2025 (GLOBE NEWSWIRE) -- KYMERA THERAPEUTICS, INC. (NASDAQ: KYMR), A CLINICAL-STAGE BIOPHARMACEUTICAL COMPANY ADVANCING A NEW CLASS OF ORAL SMALL MOLECULE DEGRADER MEDICINES FOR IMMUNOLOGICAL DISEASES, WILL REPORT THIRD QUARTER 2025 FINANCIAL RESULTS ON NOVEMBER 4, 2025. THE COMPANY WILL HOST A VIDEO CONFERENCE CALL AND WEBCAST AT 8:30 A.M. ET THAT DAY.

KYMERA THERAPEUTICS TO REPORT THIRD QUARTER 2025 FINANCIAL RESULTS ON NOVEMBER 4, 2025

KT-579, A POTENT, SELECTIVE, ORAL DEGRADER OF IRF5, DEMONSTRATED BROAD ACTIVITY ACROSS MULTIPLE PRECLINICAL MODELS OF LUPUS AND RHEUMATOID ARTHRITIS (RA), WITH ACTIVITY COMPARABLE OR SUPERIOR TO APPROVED AND CLINICALLY ACTIVE THERAPIES

KYMERA THERAPEUTICS PRESENTS NEW PRECLINICAL DATA FOR KT-579, A FIRST-IN-CLASS, ORAL IRF5 DEGRADER, AT THE AMERICAN COLLEGE OF RHEUMATOLOGY ANNUAL MEETING

WATERTOWN, MASS., SEPT. 03, 2025 (GLOBE NEWSWIRE) -- KYMERA THERAPEUTICS, INC. (NASDAQ: KYMR), A CLINICAL-STAGE BIOPHARMACEUTICAL COMPANY ADVANCING A NEW CLASS OF ORAL SMALL MOLECULE DEGRADER MEDICINES FOR IMMUNOLOGICAL DISEASES, TODAY ANNOUNCED THE APPOINTMENT OF BRIAN ADAMS, JD, AS CHIEF LEGAL OFFICER AND CORPORATE SECRETARY. MR. ADAMS IS A HIGHLY ACCOMPLISHED LEGAL EXECUTIVE WITH NEARLY TWO DECADES OF LEADERSHIP IN THE LIFE SCIENCES, SPANNING CORPORATE DEVELOPMENT, STRATEGIC PLANNING, AND GOVERNANCE. HE WILL LEAD KYMERA'S LEGAL, GOVERNANCE, AND INTELLECTUAL PROPERTY FUNCTIONS. MR. ADAMSWILL SUCCEEDELLEN CHINIARAWHO IS RETIRING FROM HER ROLE TO FOCUS ON BOARD SERVICE, MENTORING AND OTHER ADVISORY OPPORTUNITIES.

KYMERA THERAPEUTICS APPOINTS BRIAN ADAMS AS CHIEF LEGAL OFFICER AND CORPORATE SECRETARY

REPORTED POSITIVE KT-621 (STAT6) PHASE 1 HEALTHY VOLUNTEER DATA SURPASSING KYMERA'S TARGET PRODUCT PROFILE, AND FURTHER VALIDATING ITS ORAL, DUPILUMAB-LIKE PROFILE

KYMERA THERAPEUTICS ANNOUNCES SECOND QUARTER 2025 FINANCIAL RESULTS AND PROVIDES A BUSINESS UPDATE

WATERTOWN, MASS., JUNE 26, 2025 (GLOBE NEWSWIRE) -- KYMERA THERAPEUTICS, INC. (NASDAQ: KYMR), A CLINICAL-STAGE BIOPHARMACEUTICAL COMPANY ADVANCING A NEW CLASS OF ORAL SMALL MOLECULE DEGRADER MEDICINES FOR IMMUNOLOGICAL DISEASES, TODAY ANNOUNCED THE PRICING OF ITS UNDERWRITTEN PUBLIC OFFERING OF $250.8 MILLION OF SHARES OF ITS COMMON STOCK AND, IN LIEU OF COMMON STOCK TO CERTAIN INVESTORS, PRE-FUNDED WARRANTS TO PURCHASE SHARES OF ITS COMMON STOCK. KYMERA IS SELLING 5,044,500 SHARES OF COMMON STOCK AND, IN LIEU OF COMMON STOCK TO CERTAIN INVESTORS, PRE-FUNDED WARRANTS TO PURCHASE 655,500 SHARES OF COMMON STOCK IN THE OFFERING. THE SHARES OF COMMON STOCK ARE BEING SOLD AT A PUBLIC OFFERING PRICE OF $44.00 PER SHARE AND THE PRE-FUNDED WARRANTS ARE BEING SOLD AT A PUBLIC OFFERING PRICE OF $43.9999 PER PRE-FUNDED WARRANT, WHICH REPRESENTS THE PER SHARE PUBLIC OFFERING PRICE OF EACH SHARE OF COMMON STOCK, LESS THE $0.0001 PER SHARE EXERCISE PRICE FOR EACH PRE-FUNDED WARRANT. IN ADDITION, KYMERA HAS GRANTED THE UNDERWRITERS A 30-DAY OPTION TO PURCHASE UP TO AN ADDITIONAL 855,000 SHARES OF ITS COMMON STOCK AT THE PUBLIC OFFERING PRICE PER SHARE, LESS UNDERWRITING DISCOUNTS AND COMMISSIONS. THE GROSS PROCEEDS TO KYMERA FROM THE OFFERING ARE EXPECTED TO BE APPROXIMATELY $250.8 MILLION, BEFORE DEDUCTING UNDERWRITING DISCOUNTS AND COMMISSIONS AND ESTIMATED OFFERING EXPENSES PAYABLE BY KYMERA, EXCLUDING THE EXERCISE OF ANY PRE-FUNDED WARRANTS AND ASSUMING NO EXERCISE OF THE UNDERWRITERS' OPTION TO PURCHASE ADDITIONAL SHARES. ALL OF THE SECURITIES BEING SOLD IN THIS OFFERING ARE BEING OFFERED BY KYMERA. THE OFFERING IS EXPECTED TO CLOSE ON JUNE 30, 2025, SUBJECT TO THE SATISFACTION OF CUSTOMARY CLOSING CONDITIONS.

KYMERA THERAPEUTICS ANNOUNCES PRICING OF $250 MILLION PUBLIC OFFERING

WATERTOWN, MASS., JUNE 25, 2025 (GLOBE NEWSWIRE) -- KYMERA THERAPEUTICS, INC. (NASDAQ: KYMR), A CLINICAL-STAGE BIOPHARMACEUTICAL COMPANY ADVANCING A NEW CLASS OF ORAL SMALL MOLECULE DEGRADER MEDICINES FOR IMMUNOLOGICAL DISEASES, TODAY ANNOUNCED THAT IT HAS COMMENCED AN UNDERWRITTEN PUBLIC OFFERING OF $250.0 MILLION OF SHARES OF ITS COMMON STOCK AND, IN LIEU OF COMMON STOCK TO CERTAIN INVESTORS, PRE-FUNDED WARRANTS TO PURCHASE SHARES OF ITS COMMON STOCK. ALL OF THE SHARES OF COMMON STOCK AND PRE-FUNDED WARRANTS TO BE SOLD IN THIS OFFERING ARE BEING OFFERED BY KYMERA. IN ADDITION, KYMERA INTENDS TO GRANT THE UNDERWRITERS A 30-DAY OPTION TO PURCHASE UP TO AN ADDITIONAL $37.5 MILLION OF SHARES OF ITS COMMON STOCK AT THE PUBLIC OFFERING PRICE PER SHARE, LESS UNDERWRITING DISCOUNTS AND COMMISSIONS. THE PROPOSED OFFERING IS SUBJECT TO MARKET AND OTHER CONDITIONS, AND THERE CAN BE NO ASSURANCE AS TO WHETHER OR WHEN THE OFFERING MAY BE COMPLETED, OR AS TO THE ACTUAL SIZE OR TERMS OF THE OFFERING.

Kymera Therapeutics, Inc.

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