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Tango Therapeutics, Inc., a biotechnology company, discovers and develops drugs for the treatment of cancer. Its lead program is TNG908, a synthetic lethal small molecule inhibitor of protein arginine methyltransferase 5 that is being developed as a treatment for cancers with methylthioadenosine phosphorylase deletions. The company also develops Ubiquitin-specific protease 1, an inhibitor to treat patients with BRCA1 or BRCA2-mutant cancers; and Target 3 for STK11-mutant cancers. Tango Therapeutics, Inc. has a strategic collaboration with Gilead Sciences, Inc. for the discovery, development, and commercialization of a pipeline of therapies for patients with cancer. The company was founded in 2017 and is based in Cambridge, Massachusetts.

Tango Therapeutics, Inc.

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 FIRST PATIENT DOSED IN COMBINATION TRIAL OF TNG462 AND REVOLUTION MEDICINES RAS(ON) INHIBITORS   FIRST PATIENT DOSED IN PHASE 1/2 TRIAL WITH TNG456, A BRAIN-PENETRANT MTA-COOPERATIVE PRMT5 INHIBITOR IN DEVELOPMENT FOR GLIOBLASTOMA  BOSTON, AUG. 05, 2025 (GLOBE NEWSWIRE) -- TANGO THERAPEUTICS, INC. (NASDAQ: TNGX), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY COMMITTED TO DISCOVERING AND DELIVERING THE NEXT GENERATION OF PRECISION CANCER MEDICINES, TODAY REPORTED FINANCIAL RESULTS FOR THE SECOND QUARTER ENDED JUNE30, 2025, AND PROVIDED BUSINESS HIGHLIGHTS. TNG462 HAS THE POTENTIAL TO BE A BEST-IN-CLASS PRMT5 INHIBITOR FOR THE TREATMENT OF MTAP-DEL PANCREATIC AND LUNG CANCERS, AND WE LOOK FORWARD TO SHARING DATA THAT SUPPORT OUR CONVICTION LATER THIS YEAR, SAID BARBARA WEBER, M.D.

TANGO THERAPEUTICS REPORTS SECOND QUARTER 2025 FINANCIAL RESULTS AND PROVIDES BUSINESS HIGHLIGHTS

BOSTON, JUNE 27, 2025 (GLOBE NEWSWIRE) -- TANGO THERAPEUTICS, INC. (NASDAQ: TNGX), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY COMMITTED TO DISCOVERING THE NEXT GENERATION OF PRECISION CANCER MEDICINES, TODAY ANNOUNCED THAT THE FIRST PATIENT HAS BEEN DOSED IN THE PHASE 1/2 TRIAL OF TNG462 AND REVOLUTION MEDICINES' DARAXONRASIB (RAS(ON) MULTI-SELECTIVE INHIBITOR) OR ZOLDONRASIB (RAS(ON) G12D-SELECTIVE INHIBITOR) IN PATIENTS WITH MTAP-DELETED AND RAS MUTANT METASTATIC PANCREATIC OR LUNG CANCER.

TANGO THERAPEUTICS ANNOUNCES FIRST PATIENT DOSED IN PHASE 1/2 TRIAL OF TNG462 PLUS REVOLUTION MEDICINES' DARAXONRASIB OR ZOLDONRASIB IN PATIENTS WITH RAS-MUTANT MTAP-DELETED PANCREATIC OR LUNG CANCER

BOSTON, MAY 27, 2025 (GLOBE NEWSWIRE) -- TANGO THERAPEUTICS, INC.(NASDAQ: TNGX), TODAY ANNOUNCED THAT BARBARA WEBER, M.D., PRESIDENT AND CHIEF EXECUTIVE OFFICER OF TANGO THERAPEUTICS, IS SCHEDULED TO PARTICIPATE IN A FIRESIDE CHAT AT THE 46TH ANNUAL GOLDMAN SACHS GLOBAL HEALTHCARE CONFERENCE ON TUESDAY, JUNE 10 AT 3:20-3:55 PM ET.

TANGO THERAPEUTICS TO PARTICIPATE IN THE 46TH ANNUALGOLDMAN SACHSGLOBAL HEALTHCARE CONFERENCE

BOSTON, MAY 21, 2025 (GLOBE NEWSWIRE) -- TANGO THERAPEUTICS, INC. (NASDAQ: TNGX), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY COMMITTED TO DISCOVERING THE NEXT GENERATION OF PRECISION CANCER MEDICINES, TODAY ANNOUNCED THAT THE FIRST PATIENT HAS BEEN DOSED IN THE TNG456 PHASE 1/2 TRIAL IN PATIENTS WITH MTAP-DELETED SOLID TUMORS, WITH A FOCUS ON GLIOBLASTOMA (GBM). TNG456 IS A NEXT-GENERATION, BRAIN-PENETRANT, MTA-COOPERATIVE PRMT5 INHIBITOR.

TANGO THERAPEUTICS ANNOUNCES FIRST PATIENT DOSED IN TNG456 PHASE 1/2 TRIAL IN PATIENTS WITH MTAP-DELETED GLIOBLASTOMAS AND OTHER SOLID TUMORS

 DATA UPDATE FROM ONGOING TNG462 PHASE 1/2 MONOTHERAPY TRIAL EXPECTED 2H 2025  COMBINATION TRIAL OF TNG462 + REVOLUTION MEDICINES RAS(ON) INHIBITORS ON TRACK FOR ENROLLMENT 2Q 2025   CASH POSITION OF $217 MILLION AS OF MARCH 31, 2025; CASH RUNWAY EXTENDED INTO 1Q 2027 WITH REDUCTION OF PRECLINICAL SPEND  BOSTON, MAY 12, 2025 (GLOBE NEWSWIRE) -- TANGO THERAPEUTICS, INC. (NASDAQ: TNGX), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY COMMITTED TO DISCOVERING AND DELIVERING THE NEXT GENERATION OF PRECISION CANCER MEDICINES, REPORTED ITS FINANCIAL RESULTS FOR THE FIRST QUARTER ENDED MARCH31, 2025, AND PROVIDED BUSINESS HIGHLIGHTS. ACCUMULATING DATA CONTINUE TO SUPPORT TNG462 AS THE POTENTIAL BEST-IN-CLASS PRMT5 INHIBITOR, SAID BARBARA WEBER, M.D.

TANGO THERAPEUTICS REPORTS FIRST QUARTER 2025 FINANCIAL RESULTSAND PROVIDES BUSINESS HIGHLIGHTS

BOSTON, MAY 01, 2025 (GLOBE NEWSWIRE) -- TANGO THERAPEUTICS, INC. (NASDAQ: TNGX), TODAY ANNOUNCED THAT IT WILL REPORT FIRST QUARTER 2025 FINANCIAL RESULTS ON MAY 12, 2025, BEFORE THE OPEN OF THE U.S. FINANCIAL MARKETS. THE COMPANY DOES NOT INTEND TO HOLD A CONFERENCE CALL.

TANGO THERAPEUTICS TO REPORT FIRST QUARTER 2025 FINANCIAL RESULTS ON MONDAY, MAY 12, 2025

BOSTON, MARCH 25, 2025 (GLOBE NEWSWIRE) -- TANGO THERAPEUTICS, INC. (NASDAQ: TNGX), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY COMMITTED TO DISCOVERING AND DELIVERING THE NEXT GENERATION OF PRECISION CANCER MEDICINES, TODAY ANNOUNCED THAT FIVE ABSTRACTS HAVE BEEN ACCEPTED AS POSTER PRESENTATIONS AT THE AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR) ANNUAL MEETING 2025, TAKING PLACE APRIL 25-30, 2025, IN CHICAGO, ILLINOIS.

TANGO THERAPEUTICS TO HIGHLIGHT PRECLINICAL DATA ON PRECISION ONCOLOGY PIPELINE WITH FIVE POSTERS AT THE AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR) ANNUAL MEETING 2025

 TNG462 GRANTED ORPHAN DRUG DESIGNATION FOR TREATMENT OF PANCREATIC CANCER  INVESTIGATIONAL NEW DRUG (IND) APPLICATION FOR TNG456, A NEXT-GENERATION BRAIN-PENETRANT MTA-COOPERATIVE PRMT5 INHIBITOR, CLEARED BY FDA. PHASE 1/2 ENROLLMENT EXPECTED TO BEGIN 1H 2025   CLINICAL COLLABORATION WITH ELI LILLY TO EVALUATE TNG456 IN COMBINATION WITH CDK4/6 INHIBITOR VERZENIO  (ABEMACICLIB) ESTABLISHED   DATA UPDATE FROM ONGOING TNG462 MONOTHERAPY TRIAL EXPECTED IN 2025 WITH FOCUS ON PANCREATIC AND LUNG CANCER   CASH POSITION OF$258 MILLIONAS OFDECEMBER 31, 2024, WITH CASH RUNWAY EXPECTED TO FUND OPERATIONS INTO 3Q 2026  BOSTON, FEB. 27, 2025 (GLOBE NEWSWIRE) -- TANGO THERAPEUTICS, INC. (NASDAQ: TNGX), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY COMMITTED TO DISCOVERING AND DELIVERING THE NEXT GENERATION OF PRECISION CANCER MEDICINES, REPORTED FINANCIAL RESULTS FOR THE FOURTH QUARTER AND FULL YEAR ENDED DECEMBER 31, 2024, AND PROVIDED BUSINESS HIGHLIGHTS.

TANGO THERAPEUTICS REPORTS FOURTH QUARTER AND FULL YEAR 2024 FINANCIAL RESULTS AND PROVIDES BUSINESS HIGHLIGHTS

BOSTON, JAN. 30, 2025 (GLOBE NEWSWIRE) -- TANGO THERAPEUTICS, INC.(NASDAQ: TNGX), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY COMMITTED TO DISCOVERING AND DELIVERING THE NEXT GENERATION OF PRECISION CANCER MEDICINES, TODAY ANNOUNCED THAT BARBARA WEBER, M.D., PRESIDENT AND CHIEF EXECUTIVE OFFICER OF TANGO THERAPEUTICS, IS SCHEDULED TO PARTICIPATE IN A FIRESIDE CHAT AT THE GUGGENHEIM SMID CAP BIOTECHNOLOGY CONFERENCE ON WEDNESDAY, FEBRUARY 5, 2025 AT 10:00 AM ET.

TANGO THERAPEUTICS TO PRESENT AT THE GUGGENHEIM SMID CAP BIOTECHNOLOGY CONFERENCE

BOSTON--(BUSINESS WIRE)--TANGO THERAPEUTICS, INC. (NASDAQ: TNGX), A CLINICAL-STAGE BIOTECHNOLOGY COMPANY COMMITTED TO DISCOVERING AND DELIVERING THE NEXT GENERATION OF PRECISION CANCER MEDICINES, TODAY ANNOUNCED THAT, EFFECTIVE DECEMBER 2, 2024, THE COMPENSATION COMMITTEE OF TANGO THERAPEUTICS' BOARD OF DIRECTORS GRANTED A NON-QUALIFIED STOCK OPTION TO PURCHASE 187,500 SHARES OF ITS COMMON STOCK AND 31,250 RESTRICTED STOCK UNITS (RSUS) TO A NEW EMPLOYEE UNDER TANGO THERAPEUTICS' 2023 INDUCEMENT.

Tango Therapeutics, Inc.

TNGX

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Tango Therapeutics, Inc.

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TNGX